Microsoft has released SP1 for Windows Server 2008 R2. In SP1 there are several enhancements for Remote Desktop Services. Especially RemoteFX is a noticeable change. So what’s the impact on XenApp 6.0? One would expect that this also requires an update for XenApp 6.0. But when we take a closer look at RemoteFX on the server, you see that this is a separate Role Service of Remote Desktop Services. One requirement for RemoteFX is that the server must have one or more GPUs installed and it works with RDP, not with ICA. When you don’t install RemoteFX, RDS is just RDS with all hotfixes bundled in a service pack.
To support XenApp 6.0 on Windows Server 2008 R2 with SP1, just install CTX125388 – Hotfix XA600W2K8R2X64001. In http://support.citrix.com/article/CTX126711, Microsoft Windows Server 2008 R2 Service Pack 1 – Known Issues, there are no further issues reported.